If You Carry a Common MTHFR Gene Variant, Your Coffee Choice Matters More Than You Think

Let’s have an honest conversation about your health and how your body handles what you put into it. This especially includes coffee.

What Is the MTHFR Gene Variant and Why It Matters

Your body has a natural process called methylation, which supports detoxification, energy production, and mood regulation. The MTHFR gene helps your body perform this process efficiently. Many people carry a variation in this gene, such as MTHFR C677T or MTHFR A1298C. In the United States, more than half of the population carries at least one copy of a common MTHFR variant. Around the world, the numbers vary by ancestry. If your MTHFR activity is lower than normal, your body may have a harder time clearing certain toxins and byproducts of metabolism. You can find out if you carry this gene by taking the 10X Health genetic test, which provides a breakdown of methylation and detox pathways:
https://10xhealthsystem.com/genetest/

What Happens Inside Your Body When You Drink Coffee

When coffee beans are roasted, natural heat reactions create small amounts of compounds called acrylamides and polycyclic aromatic hydrocarbons, also known as PAHs. These are also found in toasted bread and grilled foods. In addition, if coffee beans are grown, stored, or transported in humid conditions, they can develop mold that produces mycotoxins. Your liver must break down and remove these substances. It does this through several detoxification pathways that depend on enzymes and nutrients created by methylation. If your MTHFR gene is less active, this process can slow down. Other genes also play a role, such as GSTM1 and GSTT1, which produce enzymes that attach toxins to glutathione so they can be safely excreted. When those genes are missing or underactive, detox becomes even harder.

Why This Matters for You

If your detox system is sluggish, your body may react more strongly to ordinary coffee. You might notice fatigue, anxiety, headaches, brain fog, or inflammation after drinking it. These reactions do not mean coffee is bad for you. They mean your body is working overtime to manage what is in it. People who are most likely to notice this include those with MTHFR variants, people with a history of mold exposure, those who live in polluted environments, or anyone who struggles with chronic inflammation.

Why Truista Coffee Was Created

Truista Coffee was built for people who care about what they put in their body. Our goal is to create coffee that complements your biology, not fights it.

Here is How We Do It

We start at the farm with a proprietary, patent-pending fermentation process that is designed to block the formation of acrylamide during roasting. Independent accredited labs have reported acrylamide at or below their method detection limits on our pilot and production lots. We source beans from trusted farms and test them for mold and mycotoxins before roasting. Our roast profile is engineered to minimize PAHs while preserving flavor and antioxidants. Every batch is verified through third-party laboratory testing for purity and safety. The result is coffee that is clean, pure, and aligned with how your body actually works.

A Healthier Choice for Your Body

If your genes make detoxification slower, your coffee should not make that harder. Truista Coffee is designed for people who want to feel sharp, energized, and supported by what they drink. When you buy your next bag of coffee, ask yourself, What is this doing for my body? Choose a brand that works with your genetics, not against them. Try Truista Coffee. Clean. Scientifically validated. Made for your biology.